Canine Vaccination Protocol (2018) – W. Jean Dodds, DVM

Note: the following vaccine protocol is offered for those dogs where minimal vaccinations are advisable. The schedule is one I recommend and should not be interpreted to mean that other protocols recommended by a veterinarian would be less satisfactory. It’s a matter of professional judgment and choice.

VaccineInitial1st Annual BoosterRe-Administration IntervalComments
Distemper (MLV) (e.g. Merck Nobivac DPV, or NeoVacD monovalent CDV only). Optional is recombinant rCDV = Merial Recombitek, but only comes in combo with CPV and Hepatitis/Adenovirus or more antigens9-10 weeks; 14-15 weeksAt 1 year MLV Distemper/ Parvovirus only, or serum DPV antibody titersNone needed. Duration of immunity 7.5 / 15 years by studies. Probably lifetime.Can have side effects if given too young (less than 8 weeks). Also can cause post-vaccinal encephalitis (PVE); see below.
Parvovirus (MLV) (e.g. Merck Nobivac DPV, or NeoPar monovalent CPV only)9-10 weeks; 14-15; 18 weeks. In endemic parvovirus outbreaks, MLV CPV vaccine can be given at 6 weeks initially; then followed up with protocol above.At 1 year MLV Distemper/ Parvovirus only, or serum DPV antibody titersNone needed. Duration of immunity 7.5 years by studies. Probably lifetime. Longer studies pending.At 6 weeks of age, less than 30% of puppies are protected but 100% are exposed to the ubiquitous CPV.
Rabies (only killed)20-24 weeks or as legally required. Use only thimerosal (mercury-free) rabies vaccine = Merial IMRAB TF-1, or Boehringer Ingelheim RabVac 1TF1 year after puppy rabies (give 3-4 weeks apart from Dist/Parvo booster) Killed 3 year thimerosal (mercury -free) rabies vaccine = Merial IMRAB TF-3, or Boehringer Ingeleim RabVac 3-TF3 yr. vaccine given as required by law in California (follow your state/provincial requirements)Rabid animals may infect dogs or any other mammal including people.

Distemper @ 6 weeks or youngerNot recommended. At this age, maternal antibodies form the mother’s milk (colostrum) will partially neutralize the vaccine, and giving MLV CDV vaccine earlier can cause vaccine-induced signs of distemper especially seizures and paralysis.
Parvovirus @ 6 weeksIn endemic parvovirus outbreaks, MLV CPV vaccine can be given at 6 weeks initially; then followed up with usual protocol above.
Hepatitis (Adenovirus 2) MLV often in a combo with CDV and CPVNot preferred. Giving MLV CDV with Adenovirus-2 causes immune suppression for up to 10 days in puppies and increases chances of post-vaccinal encephalitis (PVE). Note: Merial Recombitek combo vaccine cannot cause PVE. IF adenovirus vaccination is desired, can give to older adolescents with oral or intranasal (not injectable) Bordetella as it induces interferon that protects against the upper respiratory viruses.
CoronavirusNot recommended. Disease usually only affects young puppies that are malnourished and parasitized. Rare clinical disease. Mild self-limiting disease; produces orange-colored stool. Virus killed by 80 degrees F and dry housing.
Leptospirosis (4-Way killed vaccine)Not recommended. Rare clinical cases; a reportable zoonotic disease, so check local veterinary and public health agencies for documented cases. Vaccine side effects common. 4-way vaccine often contains the wrong serovars causing disease in local areas. There is poor cross-protection between serovars. Two doses initially needed given 3-4 weeks apart followed by yearly boosters.
Lyme Vaccine, RecombinantNot recommended. Most cases are in Northeast and around the Great Lakes. Annual booster required after initial 2-dose series.
Bordetella (Oral or Intranasal) (killed bacterin). Injectable version (not recommended)Generally not recommended. Oral preferred over intranasal, as it cannot spray vaccine around the face and those close by. Injectable not recommended as it does not release interferon to protect against the other upper respiratory viruses (kennel cough). Not 100% effective; may be required for boarding or grooming. Offer to sign written waiver to hold facility harmless instead.
Parainfluenza Vaccine (MLV)Included as part of combo vaccines; but rarely clinically important or needed.
Influenza Bi-Valent H3N2/H3N8 Killed VaccineBeing widely recommended as these viruses are highly contagious. Not recommended routinely by Dr. Dodds as disease is mild and self-limiting unless fever is very high (>104 degrees F) and for those dogs harboring Streptococcus in their respiratory tracts. Distinguished from common kennel cough which does not produce a fever unless secondary pneumonia follows in 7-10 days. Influenza produces a fever immediately. 2 doses required 3-4 weeks apart and boosted annually.
Giardia Vaccine or Ringworm VaccineNo longer available; not recommended.

Source: W. Jean Dodds, DVM

Canine Vaccination Protocol (2018) – W. Jean Dodds, DVMHemopet NutriScan 
11561 Salinaz Avenue 
Garden Grove, CA 92843

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